There was a time when tonsils an adenoids were routinely removed whenever children suffered sore throats or ear infections. That’s not true anymore and a new study finds that may be a good thing. The Danish study found that removing tonsils and adenoids in childhood increases the long-term risk of respiratory, allergic and infectious diseases. It’s said to be the first study of its kind.
The adenoids and tonsils are strategically positioned in the nose and throat to act as a first line of defense, helping to recognize airborne pathogens like bacteria and viruses, and begin the immune response to clear them from the body.
The study initiated by the Copenhagen Evolutionary Medicine program looked at the long-term effects of removing the tonsils and adenoids in childhood, compared with children who had not undergone the surgeries.
The analysis showed:
- Tonsillectomy was associated with an almost tripled relative risk — the risk for those who had the operation compared with those who didn’t — for diseases of the upper respiratory tract. These included asthma, influenza, pneumonia and chronic obstructive pulmonary disorder or COPD, the umbrella term for diseases such as chronic bronchitis and emphysema.
- The absolute risk (which takes into account how common these diseases are in the community) was also substantially increased at 18.61 percent.
- Adenoidectomy was found to be linked with a more than doubled relative risk of COPD and a nearly doubled relative risk of upper respiratory tract diseases and conjunctivitis. The absolute risk was also almost doubled for upper respiratory diseases but corresponded to a small increase for COPD, as this is a rarer condition in the community generally.
“For tonsillectomy, we found that only five people needed to have the operation to cause an extra upper respiratory disease to appear in one of those people,” said Prof. Jacobus Boomsma of the University of Copenhagen, who led the research with Professor Stephen Stearns from Yale University. The research is published in the Journal of the American Medical Association Otolaryngology Head and Neck Surgery.
“The association of tonsillectomy with respiratory disease later in life may therefore be considerable for those who have had the operation,” Boomsma said.
The study suggests that shorter-term benefits of these surgeries may not continue up to the age of 30 apart from the reduced risk for tonsillitis (for all surgeries) and sleep disorders (for adenoidectomy).
Instead, the longer-term risks for abnormal breathing, sinusitis and otitis media were either significantly higher after surgery or not significantly different.
The researchers note that there will always be a need to remove tonsils and adenoids when those conditions are severe.
“But our observed results that show increased risks for long-term diseases after surgery support delaying tonsil and adenoid removal if possible, which could aid normal immune system development in childhood and reduce these possible later-life disease risks, Dr. Byars said. “As we uncover more about the function of immune tissues and the lifelong consequences of their removal, especially during sensitive ages when the body is developing, this will hopefully help guide treatment decisions for parents and doctors.”
The team analysed a dataset from Denmark of 1,189,061 children born between 1979 and 1999, covering at least the first 10 years and up to 30 years of their life. Of the almost 1.2 million children, 17,460 had adenoidectomies, 11,830 tonsillectomy and 31, 377 had adenotonsillectomies, where both tonsils and adenoids removed. The children were otherwise healthy.